SID 7969543

Research use only, not for human use.

SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research.

SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily.

SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively.SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM.

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Others

Other Targets

Others

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868224-64-0

452.46

C24H24N2O7

>98% (HPLC)

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O=C(OCC)C(OC1=CC=CC=2C(=O)N(C=CC12)CC(=O)NC3=CC=C4OCCOC4=C3)C

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(-20℃)

With Ice Pack

≥ 2 years